Through the actions of these hormones, adipose tissue plays an important role in the regulation of glucose , cholesterol and the metabolism of sex hormones. A number of different hormones are released from adipose tissue and these are responsible for different functions within the body. Examples of these are:. Both too much and too little adipose tissue can have severe health implications. More commonly, too much adipose tissue leads to obesity, mainly from too much visceral fat.
Obesity leads to a number of serious health problems. Obesity increases the risk of developing type 2 diabetes as it causes the body to become resistant to insulin. This resistance results in high levels of blood sugar, which is bad for health. Obesity also increases the chance of developing high blood pressure, high cholesterol levels and an increased tendency for blood to clot.
All of these raise the risk of heart attacks and stroke. In eating disorders such as anorexia nervosa , the patient does not eat enough food to maintain their adipose tissues levels. This means that they can lose a dangerous amount of body weight. About Contact Events News. Adipose tissue remodeling is a complex but well-orchestrated mechanism modulated by multiple adipose tissue cell types that allow adaptation to external environmental changes.
A deeper mechanistic understanding of adipose tissue remodeling could facilitate the development of therapeutic approaches against obesity-induced metabolic diseases. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. We thank Yoon Jeong Park for critical reading and helpful comments.
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